Neonatal primary pulmonary hypertension is a serious disease that is difficult to treat, but early diagnosis and comprehensive intervention can improve prognosis. Treatment methods include drug therapy, oxygen therapy, and supportive therapy; the specific plan needs to be formulated based on the patient's condition.
1. Drug therapy is one of the main treatments for neonatal primary pulmonary hypertension. Commonly used drugs include prostaglandins such as iloprost, phosphodiesterase-5 inhibitors such as sildenafil, and endothelin receptor antagonists such as bosentan. These drugs relieve symptoms by dilating pulmonary blood vessels and reducing pulmonary artery pressure. The choice of medication should be based on the child's specific condition and the doctor's advice.
2. Oxygen therapy plays a crucial role in the treatment of neonatal primary pulmonary hypertension. By providing high concentrations of oxygen, it can improve the infant's oxygenation status and reduce the damage caused by hypoxemia. Oxygen therapy methods include nasal cannula oxygen therapy, face mask oxygen therapy, and high-flow nasal cannula oxygen therapy, with the specific method chosen based on the infant's oxygenation status and tolerance.
3. Supportive therapy is also indispensable in the treatment of neonatal primary pulmonary hypertension. This includes maintaining stable body temperature, ensuring adequate nutrition, and preventing infection. Nutritional support can be provided through breastfeeding or formula feeding, and intravenous nutrition may be necessary in some cases. Infection prevention requires attention to hand hygiene, environmental cleanliness, and avoidance of contact with sources of infection.
Treatment of neonatal primary pulmonary hypertension requires multidisciplinary collaboration, including neonatology, cardiology, and pulmonology. Early diagnosis and timely intervention are key to improving prognosis. Parents need to closely cooperate with the doctor's treatment recommendations and regularly monitor changes in the condition. Through comprehensive treatment and meticulous care, many children can achieve a good quality of life.