Treatment options for chronic glandular cholecystitis include medication, surgery, and lifestyle modifications. Its pathology primarily involves long-term inflammatory stimulation of the gallbladder mucosa, leading to glandular hyperplasia and structural changes.
Drug treatment mainly targets symptom relief and inflammation control. Commonly used drugs include antibiotics such as amoxicillin and ceftriaxone to treat infection, analgesics such as ibuprofen and acetaminophen to relieve pain, and choleretics such as ursodeoxycholic acid to promote bile excretion.
Surgical treatment is usually performed when drug treatment is ineffective or the condition is severe. Common surgeries include cholecystectomy, laparoscopic cholecystectomy, and open cholecystectomy to completely remove the diseased tissue.
Lifestyle modifications are an important part of adjunctive treatment. Patients are advised to maintain a low-fat diet, eat more high-fiber foods such as fruits and vegetables, and reduce their intake of fried foods and animal fats; engage in moderate exercise such as walking and swimming to improve physical fitness; maintain a regular schedule and avoid overwork to help control the progression of the disease; and have regular check-ups to monitor changes in the condition and adjust the treatment plan in a timely manner.
The pathological mechanism of chronic glandular cholecystitis is complex, involving multiple factors including genetics, environment, and physiology. Among genetic factors, a family history of cholecystitis increases the risk. Environmental factors such as a long-term high-fat diet, obesity, and diabetes can easily trigger inflammation. Among physiological factors, impaired gallbladder emptying and alterations in bile composition can lead to persistent inflammation. Trauma such as abdominal impact can also induce or aggravate inflammation. Pathologically, the inflammation progresses from mild to severe, eventually potentially leading to gallbladder wall thickening, fibrosis, and loss of function. Treatment methods require comprehensive consideration of the condition and individual differences to select an appropriate regimen. Regular follow-up and lifestyle modifications are crucial for disease control.