Share this

Can Lactobacillus acidophilus inhibit Helicobacter pylori?

2026-02-01 20:15:16 · · #1

Lactobacillus acidophilus has a certain inhibitory effect by regulating the balance of intestinal flora, enhancing immune function, and inhibiting the colonization of Helicobacter pylori, but it does not have a therapeutic effect of directly killing Helicobacter pylori. It is recommended to supplement the daily diet with appropriate amounts of Lactobacillus acidophilus, in conjunction with medical medication and lifestyle modifications, to improve the eradication rate of Helicobacter pylori.

1. Lactobacillus acidophilus reduces the colonization of Helicobacter pylori through a competitive inhibition mechanism. It can form a protective layer on the gastric mucosa, occupying the attachment sites of Helicobacter pylori and thus reducing its number. At the same time, the metabolites secreted by Lactobacillus acidophilus, such as lactic acid and acetic acid, can lower the pH value in the stomach, creating an environment unfavorable to the survival of Helicobacter pylori.

2. Lactobacillus acidophilus can enhance the body's immune function. It can activate immune cells such as macrophages and natural killer cells, enhancing their killing effect on Helicobacter pylori. Lactobacillus acidophilus can also stimulate the intestinal mucosa to secrete immunoglobulin A, improve the mucosal immune barrier function, and reduce the damage of Helicobacter pylori to the gastric mucosa.

3. Lactobacillus acidophilus has limited inhibitory effect on Helicobacter pylori and cannot completely replace drug treatment. Currently, the main treatment for Helicobacter pylori infection is triple or quadruple therapy, which includes a proton pump inhibitor and two antibiotics. Commonly used drugs include omeprazole, amoxicillin, and clarithromycin, and must be taken strictly according to the doctor's prescription.

4. Supplementing your daily diet with Lactobacillus acidophilus can help improve treatment effectiveness. You can consume fermented foods containing Lactobacillus acidophilus in moderation, such as yogurt and sauerkraut. At the same time, pay attention to maintaining food hygiene, avoid eating raw or cold foods, and reduce the chance of infection. It is recommended to consume 300-500ml of yogurt daily, choosing low-sugar or sugar-free products.

5. Good lifestyle habits are crucial for improving Helicobacter pylori eradication rates. Maintain a regular sleep schedule and avoid staying up late and overworking. Engage in moderate aerobic exercise, such as brisk walking or swimming, to improve physical fitness. It is recommended to do moderate-intensity exercise 3-5 times a week for 30 minutes each time. Quit smoking and limit alcohol consumption to reduce irritation to the gastric mucosa.

Lactobacillus acidophilus, as one of the probiotics in the gut, plays a certain auxiliary role in inhibiting Helicobacter pylori, but it cannot replace drug treatment. It is recommended to combine Lactobacillus acidophilus supplementation with standardized drug treatment, dietary adjustments, and lifestyle modifications under the guidance of a doctor to improve the eradication effect of Helicobacter pylori and maintain gastrointestinal health. In daily life, pay attention to food hygiene, avoid unclean food, and reduce the chance of infection.

Read next