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What causes chronic non-atrophic gastritis?

2026-02-01 21:58:34 · · #1

Treatment for chronic non-atrophic gastritis includes medication and lifestyle modifications. Its causes are mainly related to Helicobacter pylori infection, long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), and poor dietary habits. For Helicobacter pylori infection, triple therapy with antibiotics such as amoxicillin, clarithromycin, and metronidazole is commonly used. For drug-induced gastritis, the medication regimen needs to be adjusted, and gastric mucosal protectants such as sucralfate, bismuth preparations, or proton pump inhibitors such as omeprazole may be used if necessary. Dietary recommendations include avoiding spicy and greasy foods, choosing easily digestible foods such as porridge and noodles, and developing a habit of eating regularly, in moderation, and chewing thoroughly.

1. Helicobacter pylori infection is one of the main causes of chronic non-atrophic gastritis. This bacterium damages the gastric mucosal barrier, leading to an inflammatory response. Treatment requires Helicobacter pylori eradication, usually using triple therapy with amoxicillin, clarithromycin, and metronidazole, for a course of 7-14 days. After eradication, follow-up examinations are necessary to confirm the effectiveness of the treatment, and precautions should be taken to prevent reinfection, such as separate meals and sterilization of tableware.

2. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen can inhibit prostaglandin synthesis, reducing the gastric mucosa's self-protective ability and thus causing gastritis. For patients who must take NSAIDs long-term, it is recommended to use gastric mucosal protectants such as sucralfate or proton pump inhibitors such as omeprazole to reduce drug damage to the gastric mucosa. If necessary, switching to a drug with less gastrointestinal irritation can be considered.

3. Poor dietary habits such as overeating, excessive alcohol consumption, and a preference for spicy and irritating foods can directly irritate the gastric mucosa, leading to chronic inflammation. Improving dietary habits is an important measure for prevention and treatment. It is recommended to eat three meals a day at regular times and in appropriate quantities, avoiding overeating or going hungry; choose light and easily digestible foods such as porridge, noodles, and steamed eggs; chew slowly and thoroughly to reduce the mechanical stimulation of food on the gastric mucosa; quit smoking and limit alcohol consumption, and avoid stimulating drinks such as coffee and strong tea.

4. Excessive mental stress and irregular work and rest schedules are also contributing factors to chronic non-atrophic gastritis. Prolonged periods of tension and anxiety can affect gastric acid secretion and gastrointestinal motility, leading to damage to the gastric mucosa. It is recommended to relieve stress through moderate exercise such as walking or yoga, maintain a regular work and rest schedule, and ensure sufficient sleep. If necessary, seek psychological counseling and learn stress management techniques.

5. Other factors such as bile reflux and autoimmune reactions may also lead to chronic non-atrophic gastritis. For bile reflux gastritis, prokinetic drugs such as domperidone or mosapride can be used in combination with gastric mucosal protectants. Autoimmune gastritis is relatively rare and requires immunomodulatory therapy under the guidance of a doctor.

Treatment for chronic non-atrophic gastritis requires a comprehensive approach targeting the specific cause, including eradicating Helicobacter pylori, adjusting medication regimens, improving dietary habits, and alleviating stress. Patients should have regular gastroscopy checkups to monitor changes in their condition and undergo standardized treatment under the guidance of a doctor. At the same time, developing healthy lifestyle habits, such as quitting smoking and limiting alcohol consumption, maintaining regular sleep patterns, and engaging in moderate exercise, can help prevent gastritis recurrence and promote gastric mucosal repair. Patients with persistent or worsening symptoms should seek medical attention promptly to rule out the possibility of other serious gastric diseases.

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