In its pursuit of economic development, China's environment has deteriorated, leading to a rise in diseases including non-Hodgkin's lymphoma. What are the causes of non-Hodgkin's lymphoma? What are the treatment options for non-Hodgkin's lymphoma?
The causes of non-Hodgkin's lymphoma include viruses, bacteria, radiation, certain chemicals, and cleaning agents. Epstein-Barr virus (EBV) and high-incidence areas of Burkitt's lymphoma and extranodal T/NK cell lymphoma, particularly the nasal type, are also associated. T-cell lymphoma/leukemia is closely related to T-cell viral infection type I (HTLV1). Gastric mucosa-associated lymphoid tissue lymphoma is a malignant lesion caused by reactive lesions from Helicobacter pylori infection. Increased risk of developing non-Hodgkin's lymphoma includes survivors of nuclear explosions and nuclear reactor accidents, as well as cancer patients undergoing radiotherapy and chemotherapy.
Treatment of non-Hodgkin's lymphoma largely depends on its subtype. In particular, B-cell-derived NHL, except for highly malignant cases, is mostly sensitive to chemotherapy and radiotherapy, with long remission periods and high cure rates. T-cell-derived NHL, except for low-grade malignant cases, is very sensitive to radiotherapy and chemotherapy, but long-term control is difficult, and survival rates are low. However, this is only the current standard treatment. High-grade NHL, due to its high proliferation rate, is also very sensitive to chemotherapy and radiotherapy. If bone marrow or hematopoietic stem cell transplantation and intensive therapy using colony-stimulating factors can be implemented, the cure rate can be greatly improved.
The treatment process for non-Hodgkin's lymphoma can be summarized as follows: ① Phase 1 aims to remove the tumor as much as possible; ② Phase 2 focuses on restoring the patient's overall health, with particular emphasis on immune and bone marrow function; ③ Further intensive treatment is administered as needed; ④ Post-treatment, the patient's immunity needs continuous improvement. While treating the tumor, protecting the patient's health, especially their immune, bone marrow, liver, and kidney function, is also crucial.
The above is an introduction to the causes and treatments of non-Hodgkin's lymphoma. It is hoped that this information will increase everyone's understanding of non-Hodgkin's lymphoma.